Generic drug for atorvastatin Viagra in dublin ireland the primary prevention of cardiovascular disease and hypertension."
In June 2010, "the U.S. Food and Drug Administration approved the use of atorvastatin as a single agent in both the primary prevention of cardiovascular disease and the secondary prevention of nonfatal hypertension."
The Cochrane Collaboration has also studied atorvastatin for cardiovascular prevention in high-risk patients who will benefit from the drug in low-dose dosing and an additional 6,900 patients who will benefit in high-dose dosing, compared with placebo.2 Overall, atorvastatin was found to be better, but in one of the two studies with high risk patients who would benefit, atorvastatin was not better.
The following meta-analyses examined whether atorvastatin is superior to other treatments for coronary artery disease, or whether it is more efficacious than other agents for coronary artery disease other than statins or aspirin.
Heart and Stroke Trial Group. "Beneficial effects of atorvastatin in primary prevention myocardial infarction high-risk patients with risk factor profiles Atorva 25mg $46.97 - $4.7 Per pill comparable to those treated with statins, aspirin, or both statins and aspirin." (In Clinical Trial, April 2016).
Heart and Stroke Trial Group. "The safety and efficacy of atorvastatin in secondary prevention myocardial infarction: the Heart and Stroke Trial (STAR): A randomized, double-blind, parallel-group, multicenter, placebo-controlled trial." (In The Lancet, September 2014).
Atorvastatin and Heart. Diamanti-Kandarakis, B; Panagiotakos, A; Panagiotou, X; Argyrou, Arita, A. "Atorvastatin is associated with reduced incidence of ischemic chest disease in patients with cardiovascular disease." Stroke, January 2014.
"Atorvastatin may reduce mortality in ischemic heart disease patients without a history of myocardial infarction." Stroke, March 2012.
The trial by Atorvastatin, Inc. did not meet the inclusion criteria for in Cochrane Collaboration's database.
The results and conclusions in these papers have been previously published. In general, the results are limited by small sample sizes in the trials included, short follow-up periods in many of the trials, and a number of methodological issues, including not reporting all outcomes of interest to the investigators. No data can explain the drugstore gel eyeliner for oily lids clinical benefit and adverse events seen in the trials.
Evidence on the benefit/risk of atorvastatin in general is mixed, with conflicting evidence between the results of randomized trials and observational studies with varying designs and statistical analysis.
The majority of observational studies have shown that atorvastatin is associated with a lower risk of mortality and cardiovascular events, possibly attributed to effects of the drug on platelets, blood coagulation, platelet aggregation, and the effectiveness of thrombin to produce thromboelastin, while randomized trials tend to show that atorvastatin is no safer than other drugs for cardiovascular outcomes.
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